by Tom Ballard, RN, ND
Natural health experts are under tremendous pressure when treating
infectious diseases. Patients often demand their symptoms be treated with the speed and
effectiveness they've come to expect from antibiotics.
They don't want to take time
off work or be miserable. In some cases, they might not realize their infection
actually is caused by a virus or fungus. Many doctors may want to use natural treatments,
but often lack confidence when faced with what they feel is a serious infection.
Even though they have a broad array of powerful tools at their disposal, in my
opinion, doctors too often resort to prescription antibiotics.
The problem of drug antibiotics is a universal one. The entire medical community
is waking to the consequences of the overuse of antibiotics: a dramatic rise in
antibiotic-resistant organisms.
Initially, hospitals faced this problem. Now, military personnel, sports teams
and schools are seeing skin infections and respiratory diseases that resist
conventional antibiotics. "Superbugs" are a worldwide
threat.1
Holistic medicine does not have to contribute to this problem. Avoiding the use
of drug antibiotics means sticking with our fundamentals the same rules we use
when treating any disease:
- Find the cause.
- Educate the patient.
- Strengthen the patient.
- Treat the whole person.
- Utilize the healing power of nature.
Educate the Patient
Sadly, most patients don't understand much about how their immune systems work
or the differences between bacterial, fungal and viral infections. A few minutes
of education often can dissuade a patient from an unnecessary antibiotic. For
instance, according to a study out of the Mayo Clinic, most sinus infections are not
bacterial, but fungal.
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The problem of drug antibiotics is a universal one. The entire medical community is waking to the consequences of the overuse of antibiotics. |
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Strengthen the Patient
Every day, we see the advantage of working with the patient on general
lifestyle issues, including sleep, diet, stress and exercise, as well as targeted
therapies such as adrenal support, vitamin C and zinc. Two of my favorite areas to target
are the often-neglected problems of inadequate protein and skipping breakfast. As
we've all seen, basic changes can turn patients' lives
around.2
Treat the Whole Person
This is another of our strengths. We're often the only doctor the patient has
ever seen to point out the connection between their chronic eczema and recurrent respiratory
infections. And wouldn't we all like to have a dollar for every time we discussed the
connection between digestive health and the immune
system?3
Natural Antibiotics
Most practitioners have a favorite antimicrobial or two they recommend for all
the infections that walk in their door. Often, it's one they learned about in
school. Sometimes, it's whatever the last sales rep was touting. Rarely is there much
research to support their use. Fortunately, most patients recover anyway.
A Powerful New Natural Antibiotic
I've recently found a new form of an old friend that is working wonderfully
on tough infections.4 Stabilized allicin is a powerful new antimicrobial that fits
our criteria it strengthens the host, treats the whole person and utilizes the
healing power of nature. What's more, it has research to validate its effectiveness.
First, don't confuse allicin with garlic. While allicin is extracted from garlic, most
garlic and garlic products don't contain allicin. Yes, you read right: garlic and
garlic products usually do not contain
allicin.4-6
Garlic and Allicin
Garlic is the plant we all know as the universal medicine (and cooking)
ingredient. It's mentioned in all ancient medical texts and, because it has a wide growing
range, was used by all societies of the world. Garlic, and its cousin the onion, was
eaten, imbibed, gargled, applied locally and used as a suppository. It was credited
with saving people from the great plagues. In more modern times, it has been
researched and found effective for dozens of conditions. In addition to being a superb
antimicrobial, it lowers cholesterol, stabilizes blood sugar and kills cancer
cells.4-6
What's not to love about garlic? Well, maybe "garlic breath." The problem
with garlic used as a medicine always has been the instability of its active
ingredient, allicin. Allicin is the product of an enzymatic process, one of those
evolutionary miracles that helps the garlic plant survive, and humans as well.
Inside the garlic plant are tiny sacks, or vesicles. Some contain the protein
alliin. Others contain the enzyme allinase. When garlic is tampered with, either by
an invading bacterium, a worm or a kitchen knife, the two vesicles break open. The
released allinase reacts with alliin and allicin is the result. Allicin's job is to kill
instantly any invader. However, allicin is not contained in garlic; its precursor
and enzyme catalyst are.4-6
While a powerful antimicrobial, allicin's half-life is milliseconds. No need for
it to hang around in the environment. Allicin breaks down readily when subjected
to heat, light, oxygen and stomach acid. Garlic found such broad use throughout
history because it was readily available. People kept it in their kitchens woven into
garlands. It was always fresh and available to be popped in the mouth, crushed
and wrapped in a cloth or pressed into juice. But once the clove was pierced, speed
was important because the potency of allicin diminished rapidly.
Garlic in Modern Life: Allicin
With more than 5,000 medical articles attesting to the effectiveness of garlic,
why not just use the plant? Please, do. But in doing so, one must consider the
weaknesses of garlic, garlic powder and other garlic
products.4-6 The problems are:
- allicin's inherent instability;
- variation of alliin content among plants;
- inconvenience of use peeling, cutting, crushing, etc.;
- sharp taste and odor that some find offensive.
The solution to all these concerns is stabilized allicin. The process for
extracting and stabilizing allicin was developed and patented recently in England.
It's actually a fairly easy, non-solvent process. The first step is the selection of
high-quality garlic bulbs that have been tested for sufficient alliin content by HPLC
and mass spectrometry. The garlic is then crushed. Extra alliin is added to increase
the allicin production. The mixture is flooded with chilled water, frozen and then
dried under low temperature. The allicin concentrate is then packaged in a number of
ways: drops, cream, caps and as a spray. It travels easily with the patient and can be
used discreetly without leaving a taste or odor. Most importantly, the potency of
the allicin is assured.4,13
I'd like to discuss a number of questions and concerns common to allicin and
its use as medicine. What happens to the taste and smell? Unlike deodorized
garlic products, pure allicin is not "deodorized." The sulfur compounds that make
the smell also are part of what kills unfriendly microorganisms. However, even
though stabilized allicin is a sulfur compound, the odor is mild because other
volatile sulfur compounds have been removed. What slight odor does remain disappears
almost instantly because allicin is a small molecule that penetrates into cells.
Even patients using the stabilized allicin cream are not bothered by odor.
Which organisms are sensitive to allicin? Allicin has a broad range of
activity against bacteria, viruses and fungi. Both gram-positive and gram-negative
bacteria, including escherichia, salmonella, staphylococcus, streptococcus, klebsiella,
proteus, bacillus, clostridium and even Mycobacterium
tuberulosis succumb to its charms. Allicin prevents staphylococcus enterotoxins A, B and C1 formation, and has
tested effective against Helicobacter
pylori.11 Amazingly, allicin has the unique ability
to penetrate the biofilm layer that protects bacterial colonies from other
antimicrobials.7-10,12,14-15 Allicin also kills toenail and skin fungal infections, as well as
candida.4, 12 Rhinovirus, herpes and cytomegalovirus have all shown sensitivity to
garlic.12,14-15
Does allicin kill friendly gut flora? No. While some natural substances,
such as cinnamon, are lethal in high concentrations to healthy gut flora, allicin
is not. Do bacteria develop a resistance to allicin? No. In fact, the opposite
is true. Stabilized allicin is being used to treat methicillin-resistant
Staphylococcus aureus (MRSA) in England. When added to MRSA cultures, a zone of
inhibition develops.13 What success are patients having with stabilized allicin?
Prevention and treatment of flu and other viral infections with the capsules
have been reported. Toenail fungi, otherwise resistant to treatment, have
resolved. The spray has defeated sore throats. The cream works well as the topical
component to eczema and psoriasis treatment. The drops are versatile, proving
useful when directly instilled for rhinitis and sinusitis, and also for ear
infections. A recent double-blind study confirmed stabilized allicin's ability to
reduce symptoms and duration of the common cold.
Allicin is the active ingredient from the most widely used and researched
herb in the world: garlic. Studies and testimonials support allicin as a
convenient, secure way to deliver a potent anti-microbial to your patients. While
prescription antibiotics sometimes are required, all health care professionals can
avoid their unnecessary use by remembering basic naturopathic principles: finding
the cause, educating patients, strengthening the host, treating the whole
person, and utilizing natural antimicrobials.
Resources
- Livermore, D.M. Antibiotic resistance in staph in.
J of Antimicrob Agents. 2000;16:3-10.
- Farshchi, H. Deleterious effects of omitting breakfast on insulin sensitivity and fasting
lipid profiles in healthy lean women. AJCN. 2005;81:388-396.
- Gill, S. et al. Metagenomic analysis of the human distal gut microbiome, Science. June 2006; 312(5778):1355-1359.
- Josling, P. Allicin: The Heart of
Garlic. HRC Publishing: Chicago, Illinois, 2005.
- Cavalitto, C., Bailey, J.H. Allicin, the antibacterial principle of Allium sativum,
physical properties and antibacterial properties. J AM Chem Soc. 1944;86.
- Elmore, GS., Feldberg, RS. Alliin lyses localization in bundle sheaths of garlic clove, Am J Bat. 1994;81:89-94.
- Gonzalez-Fandoz, FA. Streptoyoccocal growth and enterotoxins (A-D) and thermonuclease sytheses
in the presence of dehydrated garlic. J Appl
Bacterio. 1994;77:549-552.
- Huges, EG, et al. Antimicrobial effects of Allium sativum, Allium gmeelopratrum, and Allium
cepa garlic compounds and commercial grade garlic supplements. Phytothet Res. 1991;5:154-158.
- 9. Koch, HP., Lawson, LD. Garlic, the Science and Therapeutic Application of Allium Sativum
and Related Species. Williams and Wilkins: Baltimore, 1996.
- Rabinkov, A, et al. The mode of action of allicin trapping of radicals and interaction with
thiol containing proteins. Biochem Biiophy
Acts. 1998;1379:233-234.
- Celini, GS, et al. Inhibition of Helicobacter pylori by garlic extract. FEM Immenol Med Micro. 1996;13:273-277.
- Yamada, Y., Azuma, K. Evaluation of the in vitro antifungal activity of allicin. Antimicro Agents Chemol. 1997;1:743-749.
- Cutler, R., Wilson, P. Antibacterial activity of a new stable aquous extract of allicin
against MRSA. British J of Biomedical
Science. 2004;2:61-63.
- Ankri, S., Mirelman, D. Antimicrobial properties of allicin from garlic. Microbes Infect. 1999;2:125-129.
- Block, E. The chemistry of garlic and onion. Scientific Am. 1985;252:94-99.
Tom Ballard, RN, ND, graduated from Bastyr University in 1982. He practices
family naturopathic medicine in Seattle, focusing on finding and treating the cause
of disease, and will be opening a detoxification center later this year. His
specialties are fatigue, allergies, skin and digestive problems, and chronic pain.
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